SaVanna Shoemaker
Have you heard of NMN yet? Nicotinamide mononucleotide (NMN) is a unique compound with powerful anti-aging properties. In recent years, it’s become highly sought after for people interested in cellular health and longevity. It’s important to choose an NMN supplement that’s high quality and that contains an effective dose of NMN, though. That’s why we’ve rounded up the best NMN supplements below, along with explanations of why each product made the cut.
What is NMN?
In the body, NMN is a precursor to nicotinamide adenine dinucleotide (NAD). NAD helps the body metabolize food into usable energy. It is found in all cells in the body, but declines as we age.
However, studies have found that NMN supplements can increase NAD levels. These increased NAD levels provide powerful antioxidant effects — reducing oxidative stress and essentially helping to turn back the clock on a cellular level.
Potential NMN Benefits
Because of its function as an NAD booster, NMN has several potential benefits:
- Anti-aging: NMN may support mitochondrial health, helping each cell to create more energy and function more optimally. It’s a youthful energy boost to the cells.
- Antioxidant: NMN may function as an antioxidant to help reduce oxidative stress, which improves cellular health and function.
- Anti-inflammatory: Systemic inflammation is a major contributor to several health issues (including premature aging), and NMN can help to ease inflammatory processes in stored body fat that can contribute to these problems.
NMN Uses
Because of its many potential benefits, people turn to NMN supplements to help with a variety of aging- and health-related concerns. Some of the most common reasons people use NMN include:
- Longevity and general wellbeing
- Immune health
- Mental clarity and brain health
- Skin health and appearance
- Metabolism and weight loss
- Insulin sensitivity and blood sugar control
- Fatigue
- Exercise endurance and recovery
- Mood and stress reduction
Still, much of the research on NMN is from test-tube or animal studies. The consensus around NMN may change as more data from human trials becomes available.
What is the best NMN supplement for overall health?
Best Overall: NMN Supplement by Double Wood Supplements
- Delivers 250 milligrams of NMN per serving
- Third-party tested for product quality
- Simple, effective formulation with just 3 ingredients
Double Wood Supplements NMN is a well-formulated NMN supplement that’s meticulously third-party tested for purity and quality. In just two softgel capsules, it provides 250 milligrams of NMN- a dose that’s shown anti-aging benefits in several well-designed research studies. Additionally, Double Wood NMN is also more affordable than many other NMN products and is backed by a 100% money-back guarantee.
Pros:
- Third-party tested
- More affordable than other NMN products
- Contains an effective NMN dosage
Cons:
- Not plant-based (contains gelatin)
$48.95 | at Double Wood Supplements
Best Vegan NMN Supplement: NMN Capsules by Wonderfeel
- Contains 500 milligrams of NMN per capsule
- Independently tested for quality assurance
- Made with plant-based ingredients
Wonderfeel NMN Capsuls are an excellent plant-based option, made simply from NMN, a vegan capsule, and a naturally-sourced stabilizer. Additionally, each capsule delivers an impressive 500 milligrams of NMN. For people over 40, Wonderfeel recommends a daily dose of 2 capsules per day to support mitochondrial health. Wonderfeel products are also third-party tested for quality.
Pros:
- Provides a high dose of NMN (500 milligrams/capsule)
- Vegan-friendly
- Small, easy to swallow capsules
Cons:
- No money-back guarantee
$58 | at Wonderfeel
Best NMN Supplement for Cellular Health: Cell Being by Verso
- Provides 250 milligrams of NMN per serving
- Contains other powerful anti-aging ingredients
- Third-party tested for purity and contaminants
To improve cellular health for better energy, physical performance, and mental endurance, Verso’s Cell Being is an excellent choice. It contains an evidence-backed 250 milligrams of NMN per serving, plus the potent polyphenol resveratrol and endurance-boosting trimethylglycine (TMG). Additionally, Verso’s products are third-party tested with detailed reports available for each lot on their website.
Pros:
- Formulated with NMN, resveratrol, and TMG
- Third-party tested
- Designed to boost cellular energy
Cons:
- No money-back guarantee
$60 | at Verso
Best Anti-Aging NMN Supplement: Signal by Elysium Health
- 250 milligrams of NMN per serving
- Contains a mitochondrial health complex
- NSF Certified for Sport
Signal, from Elysium Health, targets mitochondrial health to help provide systemic anti-aging benefits like increased energy, improved endurance, and better insulin sensitivity. In addition to NMN, it contains honokiol and grape vine extract to increase SIRT3 activity — which helps your cells generate new mitochondria. It’s also NSF Certified for Sport, meaning it’s free of banned substances and safe for competitive athletes.
Pros:
- Third-party tested and certified by NSF
- Contains NMN and other mitochondrial health ingredients
- Plant-based
Cons:
- No refunds for any reason
- Contains filler ingredients
$60 | at Elysium Health
Best Chewable NMN Supplement: Optima NAD Booster by Elevant
- 250 milligrams of NMN per serving
- Convenient chewable format
- Vegan and gluten-free
Sublingual NMN — which is chewable or dissolved under the tongue — can be absorbed more quickly than capsules, which must break down in the digestive tract prior to absorption. For this reason, many people prefer sublingual options — such as Elevant’s Optima NAD Booster. It provides 250 milligrams of NMN in a single, lemon-flavored chewable tablet.
Pros:
- Lemon-flavored chewable tablet
- 250 milligrams of quickly-absorbed sublingual NMN
- Gluten-free and plant-based
Cons:
- Contains artificial sweetener sucralose
- No money-back guarantee
$59.90 | at Elevant
Best Affordable NMN Supplement: NMN Powder by Bulk Supplements
- Most affordable way to purchase NMN
- Powder allows for completely customized dosing
- Free of additives
Bulk Supplements provides additive-free, independently-tested supplements in bulk, making their products some of the most affordable options available. Their NMN is no exception — a 50-gram bag contains 200 servings of 250 milligrams each for just under $30. The powder form also allows for extra-precise, customized dosing as long as you have a gram scale.
Pros:
- Pure NMN powder with no additives
- Less expensive than other NMN products
- Third-party tested
Cons:
- Gram scale needed to accurately measure out doses
$29.96 | at Bulk Supplements
Best NMN Supplement for Weight Management: Peak NMN by Lifeforce
- 375 milligrams of NMN per serving
- Contains berberine and white mulberry extract for metabolic health
- Contains lithium for mood regulation
Because of its effects on metabolism and blood sugar regulation, NMN may prove useful for people trying to lose weight. In addition to 375 milligrams of NMN, each serving of Peak NMN also contains berberine and white mulberry extract. Berberine may help reduce appetite and has earned the nickname “nature’s Ozempic.” White mulberry extract may boost weight loss on a calorie-restricted diet. This blend also contains lithium, which can help promote relaxation.
Pros:
- Plant-based and gluten-free
- Berberine and white mulberry extract may support weight loss
- Higher NMN dose than many other options
Cons:
- More expensive than other NMN products
$100 | at Lifeforce
Best NMN Supplement for Overall Health FAQs
How should I take NMN supplements?
Some NMN supplement manufacturers recommend splitting your daily dose of NMN into multiple, smaller doses taken throughout the day. It’s usually not necessary to take NMN with food, though. Be sure to consult your supplement packaging and your healthcare provider for more detailed guidance.
What are the potential side effects of NMN supplements?
NMN supplements are safe for most people, but have been linked to minor side effects like skin rash or redness, gastrointestinal discomfort, increased blood sugar levels and increased uric acid levels.
What is the difference between NMN, NR, and NAD?
NMN and nicotinamide riboside (NR) are both precursors to NAD. Because NMN is currently being studied for its potential as a medication, large retailers like Amazon have stopped selling NMN supplements in order to be compliant with Food & Drug Administration (FDA) guidance. NR supplements are a more widely available NMN alternative, although NMN is still available to purchase directly through manufacturer websites.
How do I choose the best NMN supplement?
The best NMN supplements are third-party tested, formulated with effective doses of at least 250 milligrams of NMN per serving, and are made with simple, naturally-derived ingredients.
How long does it take to see results from NMN supplements?
How long it takes to see results can vary depending on a number of factors — including the dosage of your NMN supplement, how consistently you take it, and what result you’re hoping to see. Generally, it’s a good idea to take a supplement consistently for at least a month to see if it has any effects.
Can NMN supplements interact with other medications?
It’s not currently known if there are interactions between NMN and any medications. However, it is possible that interactions exist that haven’t been identified yet. Be sure to discontinue NMN and consult your doctor if you suspect it is interacting with one of your medications.
Conclusion
NMN is an NAD booster that can help your cells act younger, potentially helping you have more energy, easier exercise recovery, better mental clarity, and more. It shows a lot of promise, but it’s still important to choose the right product. Look for options that are third-party tested and that contain at least 250 milligrams of NMN per serving, from brands that stand behind their products with a money-back guarantee.
About the Author:
SaVanna Shoemaker, MS, RDN, LD, is a registered dietitian with over a decade of experience in the field of nutrition and wellness. Her expertise in holistic health and passion for research-driven content have made her a trusted voice in the wellness community. With a Master’s degree in Human Nutrition and years of clinical experience, she offers a balanced and knowledgeable approach to dietary supplements like NMN. SaVanna’s insights help readers make informed decisions about their health. When she’s not writing, she’s likely in her garden or reading the latest on nutrition science.