The diagnosed-positive individual here is Martha (Lisa Owen), a suburban single mother of four, and her progressing disease is very much a family affair. During one of her regular, intermittent hospital stays, she meets Claudia (Ximena Ayala, whose reserved performance is enchanting), a clever but directionless 20-something of the combat boot–wearing variety. The bond between the women develops when Claudia moves into Martha's home as a glorified nanny/surrogate mother to her children, a heartbreaking foreshadowing of a role made increasingly clear as the matriarch's health continues to deteriorate.
But Sainte-Luce primes the story with enough comedy to avoid total doom and gloom. The scene in which the prepubescent Mariana (Andrea Baeza) gets drunk for the first time in a Walmart-like superstore, as is young Armando's (Alejandro Ramírez-Muñoz) habit of taking his pet fish out for walks. Make no mistake, The Amazing Catfish is a tear jerker, but ultimately it's more about finding a family than losing one.